Arthrogryposis multiplex congenita (AMC), or arthrogryposis, involves congenital joint curvature in two or more areas of the body. The name translated from is Greek is literally “Hooking Joints.” It causes abnormal fibrosis of the muscle tissue, resulting in shortened muscles and preventing extending or flexing of the affected joints. There are three types of Arthogryposis: amyoplasia, distal arthrogryposis, and syndromic. Amyoplasia features severe joint contractures and muscle weakness. Distal arthrogryposis mainly involves the hands and feet. Syndromic is a primary neurological or muscle disease.

It may also be called Autosomal Recessive Amyoplasia.

For more information on Arthrogryposis multiplex congenita (AMC), visit:

• AANEM.org – Arthrogryposis Multiplex Congenita
• NORD (National Organization of Rare Diseases) Arthrogryposis Multiplex Congenita abstract
• WebMD – Arthrogryposis Mulitplex Congenita

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