What is MMIHS (Berdon Syndrome)?

Mar 23, 2015 | Diagnoses, Stories

Megacystis microcolon intestinal hypoperistalsis syndrome (MMIH Syndrome, MMIHS, or Berdon Syndrome) is a rare prenatal diagnosis involving a dilated urinary bladder which causes massive abdominal distension, microcolon and decreased or absent intestinal function. MMIHS is an autosomal recessive disorder most often occurring in females.

The prognosis and life expectancy of this generally fatal disease remains poor. Death is mainly caused by sepsis, malnutrition or multiple organ failure. This diagnosis should not be confused with prune belly syndrome or the much milder chronic idiopathic intestinal pseudo-obstruction, in which megacystis is also present.


To learn more visit:

Orphanet—Megacystisis Microcolon Intestinal Hypoperistalsis

Radiopaedia —Megacystisis Microcolon Intestinal Hypoperistalis 

Rare Diseases—MMIH Syndrome


Ending a Wanted Pregnancy stories tagged MMIHS

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